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SEPT6 Antibody

Product Specifications

Background

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

NCBI Gene ID

23157

Swiss Prot

Q14141

Accession Number

Q14141

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human SEPT6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SEPT6

NCBI Official Name

Septin-6

NCBI Organism

Homo sapiens

Background Reference 01

Ding, X., et al. J. Biochem. Mol. Biol. 40 (6) :973-978 (2007)

Background Reference 02

Sirajuddin, M., et al. Nature 449 (7160) :311-315 (2007)

Background Reference 03

Kremer, B.E., et al. Cell 130 (5) :837-850 (2007)

Background Reference 04

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Other Product Names

Septin-6, SEPT6, KIAA0128, SEP2

Tested Applications

WB

Protein ID

20178343

Physical Properties

Liquid

Frequently Asked Questions

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