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ARHGEF4 Antibody

Product Specifications

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.

NCBI Gene ID

10193024150649

Swiss Prot

Q9NR80

Accession Number

Q9NR80

Host

Rabbit

Reactivity

Human

Immunogen

This ARHGEF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-599 amino acids from the C-terminal region of human ARHGEF4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

79 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARHGEF4

NCBI Official Name

Rho guanine nucleotide exchange factor 4

NCBI Organism

Homo sapiens

Background Reference 01

Lyons, R., et al. Leuk. Res. 34 (1) :109-115 (2010)

Background Reference 02

Kawasaki, Y., et al. J. Biol. Chem. 284 (33) :22436-22443 (2009)

Background Reference 03

Itoh, R.E., et al. J. Cell. Sci. 121 (PT 16), 2635-2642 (2008) :

Background Reference 04

Kurzik-Dumke, U., et al. Cell. Signal. 19 (9) :1973-1985 (2007)

Other Product Names

Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1, ARHGEF4, KIAA1112

Tested Applications

WB

Protein ID

229463003

Physical Properties

Liquid

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