FZD3 Antibody
Product Specifications
Background
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
NCBI Gene ID
7976
Swiss Prot
Q9NPG1
Accession Number
Q9NPG1
Host
Rabbit
Reactivity
Human
Immunogen
This FZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-525 amino acids from the C-terminal region of human FZD3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FZD3
NCBI Official Name
Frizzled-3
NCBI Organism
Homo sapiens
Background Reference 01
Inkster, B., et al. Neuroimage 53 (3) :908-917 (2010)
Background Reference 02
Kawano, Y., et al. Br. J. Cancer 100 (7) :1165-1174 (2009)
Background Reference 03
Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) :
Background Reference 04
Wang, H.X., et al. Mol. Hum. Reprod. 15 (1) :11-17 (2009)
Other Product Names
Frizzled-3, Fz-3, hFz3, FZD3
Tested Applications
WB
Protein ID
17433071
Physical Properties
Liquid
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