FZD3 Antibody

Product Specifications

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.

NCBI Gene ID

7976

Swiss Prot

Q9NPG1

Accession Number

Q9NPG1

Host

Rabbit

Reactivity

Human

Immunogen

This FZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-525 amino acids from the C-terminal region of human FZD3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FZD3

NCBI Official Name

Frizzled-3

NCBI Organism

Homo sapiens

Background Reference 01

Inkster, B., et al. Neuroimage 53 (3) :908-917 (2010)

Background Reference 02

Kawano, Y., et al. Br. J. Cancer 100 (7) :1165-1174 (2009)

Background Reference 03

Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) :

Background Reference 04

Wang, H.X., et al. Mol. Hum. Reprod. 15 (1) :11-17 (2009)

Other Product Names

Frizzled-3, Fz-3, hFz3, FZD3

Tested Applications

Protein ID

17433071

Physical Properties

Liquid

Curated Selection

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