APOB48R Antibody

Product Specifications

Background

Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) -rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq].

NCBI Gene ID

55911

Swiss Prot

Q0VD83

Accession Number

Q0VD83

Host

Rabbit

Reactivity

Human

Immunogen

This APOB48R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 596-622 amino acids from the Central region of human APOB48R.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

115 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

APOBR

NCBI Official Name

Apolipoprotein B receptor

NCBI Organism

Homo sapiens

Background Reference 01

Kawakami, A., et al. Arterioscler. Thromb. Vasc. Biol. 25 (2) :424-429 (2005)

Background Reference 02

Fujita, Y., et al. J. Hum. Genet. 50 (4) :203-209 (2005)

Background Reference 03

Brown, M.L., et al. Proc. Natl. Acad. Sci. U.S.A. 97 (13) :7488-7493 (2000)

Other Product Names

Apolipoprotein B receptor, Apolipoprotein B-100 receptor, Apolipoprotein B-48 receptor, Apolipoprotein B48 receptor, apoB-48R, APOBR, APOB48R

Tested Applications

Protein ID

519668661

Physical Properties

Liquid

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