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SEC23B Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene.

NCBI Gene ID

10483

Swiss Prot

Q15437

Accession Number

Q15437

Host

Rabbit

Reactivity

Human

Immunogen

This SEC23B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the C-terminal region of human SEC23B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

86 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SEC23B

NCBI Official Name

Protein transport protein Sec23B

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Fermo, E., et al. Blood Cells Mol. Dis. 45 (1) :20-22 (2010)

Background Reference 03

Bianchi, P., et al. Hum. Mutat. 30 (9) :1292-1298 (2009)

Background Reference 04

Schwarz, K., et al. Nat. Genet. 41 (8) :936-940 (2009)

Other Product Names

Protein transport protein Sec23B, SEC23-related protein B, SEC23B

Tested Applications

WB

Protein ID

20141794

Physical Properties

Liquid

Curated Selection

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