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LAX1 Antibody

Product Specifications

Background

LAX1 negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and BCR (B-cell antigen receptor) -mediated signaling in B-cells.

NCBI Gene ID

54900

Swiss Prot

Q8IWV1

Accession Number

Q8IWV1

Host

Rabbit

Reactivity

Human

Immunogen

This LAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human LAX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LAX1

NCBI Official Name

Lymphocyte transmembrane adapter 1

NCBI Organism

Homo sapiens

Background Reference 01

Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

Background Reference 02

Shapiro, M.J., et al. J. Immunol. 181 (10) :7055-7061 (2008)

Background Reference 03

Zhu, M., et al. J. Immunol. 174 (9) :5612-5619 (2005)

Background Reference 04

Zhu, M., et al. J. Biol. Chem. 277 (48) :46151-46158 (2002)

Other Product Names

Lymphocyte transmembrane adapter 1, Linker for activation of X cells, Membrane-associated adapter protein LAX, LAX1, LAX

Tested Applications

WB

Protein ID

74728197

Physical Properties

Liquid

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