PGLYRP1 Antibody

Product Specifications

Background

PGLYRP1 is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.

NCBI Gene ID

8993

Swiss Prot

O75594

Accession Number

O75594

Host

Rabbit

Reactivity

Human

Immunogen

This PGLYRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human PGLYRP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PGLYRP1

NCBI Official Name

Peptidoglycan recognition protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 03

Dukhanina, E.A., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (33) :13963-13967 (2009)

Background Reference 04

Rohatgi, A., et al. Atherosclerosis 203 (2) :569-575 (2009)

Other Product Names

Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP, TNFSF3L

Tested Applications

Physical Properties

Liquid

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