HIRIP3 Antibody
Product Specifications
Background
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism.
NCBI Gene ID
8479
Swiss Prot
Q9BW71
Accession Number
Q9BW71
Host
Rabbit
Reactivity
Human
Immunogen
This HIRIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the Central region of human HIRIP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HIRIP3
NCBI Official Name
HIRA-interacting protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Kumar, R.A., et al. PLoS ONE (2), E4582 (2009) :
Background Reference 02
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Background Reference 03
Assrir, N., et al. Biol. Chem. 388 (4) :391-398 (2007)
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
HIRA-interacting protein 3, HIRIP3
Tested Applications
WB
Protein ID
116242511
Physical Properties
Liquid
Frequently Asked Questions
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