MPPE1 Antibody

Product Specifications

Background

Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.

NCBI Gene ID

65258

Swiss Prot

Q53F39

Accession Number

Q53F39

Host

Rabbit

Reactivity

Human

Immunogen

This MPPE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human MPPE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MPPE1

NCBI Official Name

Metallophosphoesterase 1

NCBI Organism

Homo sapiens

Background Reference 01

Lohoff, F.W., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (3), 830-836 (2010) :

Background Reference 02

Fujita, M., et al. Cell 139 (2) :352-365 (2009)

Background Reference 03

Yosifova, A., et al.Affect Disord 117 (1-2), 87-97 (2009) :

Background Reference 04

Fortna, A., et al. PLoS Biol. (7), E207 (2004) :

Other Product Names

Metallophosphoesterase 1, 31--, Post-GPI attachment to proteins factor 5, MPPE1, PGAP5

Tested Applications

Protein ID

215274110

Physical Properties

Liquid

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