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ZWILCH Antibody

Product Specifications

Background

Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.

NCBI Gene ID

55055

Swiss Prot

Q9H900

Accession Number

Q9H900

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ZWILCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-508 amino acids from the C-terminal region of human ZWILCH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

67 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZWILCH

NCBI Official Name

Protein zwilch homolog

NCBI Organism

Homo sapiens

Background Reference 01

Brendle, A., et al. Eur. J. Cancer 45 (3) :435-442 (2009)

Background Reference 02

Kops, G.J., et al. J. Cell Biol. 169 (1) :49-60 (2005)

Background Reference 03

Williams, B.C., et al. Mol. Biol. Cell 14 (4) :1379-1391 (2003)

Other Product Names

Protein zwilch homolog, hZwilch, ZWILCH

Tested Applications

WB

Protein ID

166228729

Physical Properties

Liquid

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