ZWILCH Antibody
Product Specifications
Background
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.
NCBI Gene ID
55055
Swiss Prot
Q9H900
Accession Number
Q9H900
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ZWILCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-508 amino acids from the C-terminal region of human ZWILCH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ZWILCH
NCBI Official Name
Protein zwilch homolog
NCBI Organism
Homo sapiens
Background Reference 01
Brendle, A., et al. Eur. J. Cancer 45 (3) :435-442 (2009)
Background Reference 02
Kops, G.J., et al. J. Cell Biol. 169 (1) :49-60 (2005)
Background Reference 03
Williams, B.C., et al. Mol. Biol. Cell 14 (4) :1379-1391 (2003)
Other Product Names
Protein zwilch homolog, hZwilch, ZWILCH
Tested Applications
WB
Protein ID
166228729
Physical Properties
Liquid
Curated Selection
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