LHX8 Antibody

Product Specifications

Background

Members of the LIM homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the LIM homeobox gene family are required for the patterning or the specification and differentiation of different cell types during embryonic development (Zhao et al., 1999 [PubMed 10611327]) .

NCBI Gene ID

431707

Swiss Prot

Q68G74

Accession Number

Q68G74

Host

Rabbit

Reactivity

Human

Immunogen

This LHX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human LHX8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LHX8

NCBI Official Name

LIM/homeobox protein Lhx8

NCBI Organism

Homo sapiens

Background Reference 01

Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)

Background Reference 02

Jagomagi, T., et al. Eur. J. Oral Sci. 118 (3) :213-220 (2010)

Background Reference 03

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 04

Vieira, A.R., et al. Genet. Med. 10 (9) :668-674 (2008)

Other Product Names

LIM/homeobox protein Lhx8, LIM homeobox protein 8, LHX8

Tested Applications

Protein ID

296434566

Physical Properties

Liquid

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