CCBL1 Antibody

Product Specifications

Background

This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

NCBI Gene ID

883

Swiss Prot

Q16773

Accession Number

Q16773

Host

Rabbit

Reactivity

Human

Immunogen

This CCBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-355 amino acids from the C-terminal region of human CCBL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCBL1

NCBI Official Name

Kynurenine--oxoglutarate transaminase 1

NCBI Organism

Homo sapiens

Background Reference 01

Han, Q., et al. J. Med. Chem. 52 (9) :2786-2793 (2009)

Background Reference 02

Cooper, A.J., et al. Arch. Biochem. Biophys. 474 (1) :72-81 (2008)

Background Reference 03

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 04

Kapoor, R., et al. Brain Res. 1106 (1) :205-210 (2006)

Other Product Names

Kynurenine--oxoglutarate transaminase 1, Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase I, KATI, Kynurenine--oxoglutarate transaminase I, CCBL1