ZSWIM2 Antibody

Product Specifications

Background

E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3-and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes (By similarity) .

NCBI Gene ID

151112

Swiss Prot

Q8NEG5

Accession Number

Q8NEG5

Host

Rabbit

Reactivity

Human

Immunogen

This ZSWIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 435-462 amino acids from the C-terminal region of human ZSWIM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZSWIM2

NCBI Official Name

E3 ubiquitin-protein ligase ZSWIM2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)

Background Reference 03

Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)

Background Reference 04

Nishito, Y., et al. Biochem. J. 396 (3) :411-417 (2006)

Other Product Names

E3 ubiquitin-protein ligase ZSWIM2, 632-, MEKK1-related protein X, MEX, ZZ-type zinc finger-containing protein 2, Zinc finger SWIM domain-containing protein 2, ZSWIM2, ZZZ2