FCRL1 Antibody
Product Specifications
Background
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
115350
Swiss Prot
Q96LA6
Accession Number
Q96LA6
Host
Rabbit
Reactivity
Human
Immunogen
This FCRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-392 amino acids from the C-terminal region of human FCRL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FCRL1
NCBI Official Name
Fc receptor-like protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Kazemi, T., et al. Cancer Immunol. Immunother. 58 (6) :989-996 (2009)
Background Reference 04
Kazemi, T., et al. Int. J. Cancer 123 (9) :2113-2119 (2008)
Other Product Names
Fc receptor-like protein 1, FcR-like protein 1, FcRL1, Fc receptor homolog 1, FcRH1, IFGP family protein 1, hIFGP1, Immune receptor translocation-associated protein 5, CD307a, FCRL1, FCRH1, IFGP1, IRTA5
Tested Applications
WB
Protein ID
74760931
Physical Properties
Liquid
Frequently Asked Questions
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