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FBXL19 Antibody

Product Specifications

Background

Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM].

NCBI Gene ID

54620

Swiss Prot

Q6PCT2

Accession Number

Q6PCT2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FBXL19

NCBI Official Name

F-box/LRR-repeat protein 19

NCBI Organism

Homo sapiens

Background Reference 01

Martin, J., et al. Nature 432 (7020) :988-994 (2004)

Background Reference 02

Katoh, M., et al. Int. J. Mol. Med. 14 (6) :1109-1114 (2004)

Background Reference 03

Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)

Other Product Names

F-box/LRR-repeat protein 19, F-box and leucine-rich repeat protein 19, FBXL19, FBL19

Tested Applications

WB

Protein ID

322510127

Physical Properties

Liquid

Frequently Asked Questions

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