FBXL19 Antibody
Product Specifications
Background
Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM].
NCBI Gene ID
54620
Swiss Prot
Q6PCT2
Accession Number
Q6PCT2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FBXL19
NCBI Official Name
F-box/LRR-repeat protein 19
NCBI Organism
Homo sapiens
Background Reference 01
Martin, J., et al. Nature 432 (7020) :988-994 (2004)
Background Reference 02
Katoh, M., et al. Int. J. Mol. Med. 14 (6) :1109-1114 (2004)
Background Reference 03
Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)
Other Product Names
F-box/LRR-repeat protein 19, F-box and leucine-rich repeat protein 19, FBXL19, FBL19
Tested Applications
WB
Protein ID
322510127
Physical Properties
Liquid
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