EXOSC1 Antibody
Product Specifications
Background
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly (A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
NCBI Gene ID
51013
Swiss Prot
Q9Y3B2
Accession Number
Q9Y3B2
Host
Rabbit
Reactivity
Human
Immunogen
This EXOSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the C-terminal region of human EXOSC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EXOSC1
NCBI Official Name
Exosome complex component CSL4
NCBI Organism
Homo sapiens
Background Reference 01
Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)
Background Reference 02
Lehner, B., et al. Genome Res. 14 (7) :1315-1323 (2004)
Background Reference 03
Deloukas, P., et al. Nature 429 (6990) :375-381 (2004)
Background Reference 04
Raijmakers, R., et al. J. Mol. Biol. 323 (4) :653-663 (2002)
Other Product Names
Exosome complex component CSL4, Exosome component 1, EXOSC1, CSL4
Tested Applications
WB
Protein ID
14285410
Physical Properties
Liquid
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