PKNOX2 Antibody

Product Specifications

Background

Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]) .

NCBI Gene ID

63876

Swiss Prot

Q96KN3

Accession Number

Q96KN3

Host

Rabbit

Reactivity

Human

Immunogen

This PKNOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-324 amino acids from the Central region of human PKNOX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PKNOX2

NCBI Official Name

Homeobox protein PKNOX2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. (2009) In press :

Other Product Names

Homeobox protein PKNOX2, Homeobox protein PREP-2, PBX/knotted homeobox 2, PKNOX2, PREP2

Tested Applications

Protein ID

115311621

Physical Properties

Liquid

Curated Selection

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