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SSX3 Antibody

Product Specifications

Background

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.

NCBI Gene ID

10214

Swiss Prot

Q99909

Accession Number

Q99909

Host

Rabbit

Reactivity

Human

Immunogen

This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SSX3

NCBI Official Name

Protein SSX3

NCBI Organism

Homo sapiens

Background Reference 01

Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

Background Reference 02

Gure, A.O., et al. Int. J. Cancer 101 (5) :448-453 (2002)

Background Reference 03

De Bruijn, D.R., et al. Genes Chromosomes Cancer 34 (3) :285-298 (2002)

Background Reference 04

Gure, A.O., et al. Int. J. Cancer 72 (6) :965-971 (1997)

Other Product Names

Protein SSX3, Cancer/testis antigen 53, CT53, SSX3

Tested Applications

WB

Protein ID

84028266

Physical Properties

Liquid

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