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NXF5 Antibody

Product Specifications

Background

This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo.

NCBI Gene ID

55998

Swiss Prot

Q9H1B4

Accession Number

Q9H1B4

Host

Rabbit

Reactivity

Human

Immunogen

This NXF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NXF5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-840

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NXF5

NCBI Official Name

Nuclear RNA export factor 5

NCBI Organism

Homo sapiens

Background Reference 01

Tarpey, P.S., et al. Nat. Genet. 41 (5) :535-543 (2009)

Background Reference 02

Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :

Background Reference 03

Frints, S.G., et al. Am. J. Med. Genet.119A (3), 367-374 (2003) :

Background Reference 04

Jun, L., et al. Curr. Biol. 11 (18) :1381-1391 (2001)

Other Product Names

Nuclear RNA export factor 5, TAP-like protein 1, TAPL-1, NXF5, TAPL1

Tested Applications

WB

Protein ID

20978537

Physical Properties

Liquid

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