NXF5 Antibody
Product Specifications
Background
This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo.
NCBI Gene ID
55998
Swiss Prot
Q9H1B4
Accession Number
Q9H1B4
Host
Rabbit
Reactivity
Human
Immunogen
This NXF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NXF5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NXF5
NCBI Official Name
Nuclear RNA export factor 5
NCBI Organism
Homo sapiens
Background Reference 01
Tarpey, P.S., et al. Nat. Genet. 41 (5) :535-543 (2009)
Background Reference 02
Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :
Background Reference 03
Frints, S.G., et al. Am. J. Med. Genet.119A (3), 367-374 (2003) :
Background Reference 04
Jun, L., et al. Curr. Biol. 11 (18) :1381-1391 (2001)
Other Product Names
Nuclear RNA export factor 5, TAP-like protein 1, TAPL-1, NXF5, TAPL1
Tested Applications
WB
Protein ID
20978537
Physical Properties
Liquid
Curated Selection
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