TXNDC5 Antibody

Product Specifications

Background

This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene.

NCBI Gene ID

81567

Swiss Prot

Q8NBS9

Accession Number

Q8NBS9

Host

Rabbit

Reactivity

Human

Immunogen

This TXNDC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human TXNDC5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TXNDC5

NCBI Official Name

Thioredoxin domain-containing protein 5

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, L., et al. J. Cancer Res. Clin. Oncol. 136 (10) :1497-1505 (2010)

Background Reference 02

Jeong, K.H., et al. Br. J. Dermatol. 162 (4) :759-764 (2010)

Background Reference 03

Charlton, H.K., et al. Biochem. Biophys. Res. Commun. 392 (2) :234-239 (2010)

Background Reference 04

So, H.C., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 103-113 (2010) :

Other Product Names

Thioredoxin domain-containing protein 5, Endoplasmic reticulum resident protein 46, ER protein 46, ERp46, Thioredoxin-like protein p46, TXNDC5, TLP46

Tested Applications

Protein ID

29839560

Physical Properties

Liquid

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