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HAUS8 Antibody

Product Specifications

Background

HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]) .

NCBI Gene ID

93323

Swiss Prot

Q9BT25

Accession Number

Q9BT25

Host

Rabbit

Reactivity

Human

Immunogen

This HAUS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human HAUS8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HAUS8

NCBI Official Name

HAUS augmin-like complex subunit 8

NCBI Organism

Homo sapiens

Background Reference 01

Wu, G., et al. Mol. Biol. Cell 20 (22) :4686-4695 (2009)

Background Reference 02

Lawo, S., et al. Curr. Biol. 19 (10) :816-826 (2009)

Background Reference 03

Uehara, R., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (17) :6998-7003 (2009)

Background Reference 04

Wu, G., et al. Mol. Cell. Biol. 28 (11) :3652-3662 (2008)

Other Product Names

HAUS augmin-like complex subunit 8, HEC1/NDC80-interacting centrosome-associated protein 1, Sarcoma antigen NY-SAR-48, HAUS8, HICE1

Tested Applications

WB

Protein ID

229462967

Physical Properties

Liquid

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