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FADS3 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

NCBI Gene ID

3995

Swiss Prot

Q9Y5Q0

Accession Number

Q9Y5Q0

Host

Rabbit

Reactivity

Human

Immunogen

This FADS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-355 amino acids from the C-terminal region of human FADS3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FADS3

NCBI Official Name

Fatty acid desaturase 3

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Mathias, R.A., et al. J. Lipid Res. 51 (9) :2766-2774 (2010)

Background Reference 03

Barber, M.J., et al. PLoS ONE (3), E9763 (2010) :

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Fatty acid desaturase 3, 11419-, Cytochrome b5-related protein, FADS3, CYB5RP

Tested Applications

WB

Protein ID

74762790

Physical Properties

Liquid

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