DUS2L Antibody

Product Specifications

Background

Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]) .

NCBI Gene ID

54920

Swiss Prot

Q9NX74

Accession Number

Q9NX74

Host

Rabbit

Reactivity

Human

Immunogen

This DUS2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the C-terminal region of human DUS2L.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DUS2

NCBI Official Name

TRNA-dihydrouridine (20) synthase [NAD (P) +]-like

NCBI Organism

Homo sapiens

Background Reference 01

Mittelstadt, M., et al. Nucleic Acids Res. 36 (3) :998-1008 (2008)

Background Reference 02

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Background Reference 03

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 04

Kato, T., et al. Cancer Res. 65 (13) :5638-5646 (2005)

Other Product Names

TRNA-dihydrouridine (20) synthase [NAD (P) +]-like, 131-, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2, DUS2L