PPP1R3B Antibody
Product Specifications
Background
The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA; MIM 176875) is regulated by targeting subunits, such as PP1R3B. PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e., inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and enhances the rate at which it activates glycogen synthase (see GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]) .[supplied by OMIM].
NCBI Gene ID
79660
Swiss Prot
Q86XI6
Accession Number
Q86XI6
Host
Rabbit
Reactivity
Human
Immunogen
This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-734
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP1R3B
NCBI Official Name
Protein phosphatase 1 regulatory subunit 3B
NCBI Organism
Homo sapiens
Background Reference 01
Montori-Grau, M., et al. Biochem. J. 405 (1) :107-113 (2007)
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Ceulemans, H., et al. Bioessays 24 (4) :371-381 (2002)
Background Reference 04
Doherty, M.J., et al. FEBS Lett. 375 (3) :294-298 (1995)
Other Product Names
Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4
Tested Applications
WB
Protein ID
74727837
Physical Properties
Liquid
Curated Selection
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