PPP1R3B Antibody

Product Specifications

Background

The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA; MIM 176875) is regulated by targeting subunits, such as PP1R3B. PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e., inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and enhances the rate at which it activates glycogen synthase (see GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]) .[supplied by OMIM].

NCBI Gene ID

79660

Swiss Prot

Q86XI6

Accession Number

Q86XI6

Host

Rabbit

Reactivity

Human

Immunogen

This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP1R3B

NCBI Official Name

Protein phosphatase 1 regulatory subunit 3B

NCBI Organism

Homo sapiens

Background Reference 01

Montori-Grau, M., et al. Biochem. J. 405 (1) :107-113 (2007)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Ceulemans, H., et al. Bioessays 24 (4) :371-381 (2002)

Background Reference 04

Doherty, M.J., et al. FEBS Lett. 375 (3) :294-298 (1995)

Other Product Names

Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4