LRRC16A Antibody

Product Specifications

Background

LRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) .

NCBI Gene ID

55604

Swiss Prot

Q5VZK9

Accession Number

Q5VZK9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This LRRC16A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1152-1178 amino acids from the C-terminal region of human LRRC16A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

152 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LRRC16A

NCBI Official Name

Leucine-rich repeat-containing protein 16A

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Polasek, O., et al. Croat. Med. J. 51 (1) :32-39 (2010)

Background Reference 03

Gunjaca, G., et al. Croat. Med. J. 51 (1) :23-31 (2010)

Background Reference 04

Van der Harst, P., et al. Hum. Mol. Genet. 19 (2) :387-395 (2010)

Other Product Names

Leucine-rich repeat-containing protein 16A, CARMIL homolog, LRRC16A, CARMIL, CARMIL1a, LRRC16

Tested Applications

Protein ID

74762279

Physical Properties

Liquid

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