FGF19 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.

NCBI Gene ID

9965

Swiss Prot

O95750

Accession Number

O95750

Host

Rabbit

Reactivity

Human

Immunogen

This FGF19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the C-terminal region of human FGF19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FGF19

NCBI Official Name

Fibroblast growth factor 19

NCBI Organism

Homo sapiens

Background Reference 01

Rao, A.S., et al. Gastroenterology 139 (5) :1549-1558 (2010)

Background Reference 02

Turnbull, C., et al. Nat. Genet. 42 (6) :504-507 (2010)

Background Reference 03

Schreuder, T.C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (3), G440-G445 (2010) :

Background Reference 04

Reiche, M., et al. Horm. Metab. Res. 42 (3) :178-181 (2010)

Other Product Names

Fibroblast growth factor 19, FGF-19, FGF19

Tested Applications

Physical Properties

Liquid

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