UGT2B7 Antibody

Product Specifications

Background

The UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.

NCBI Gene ID

7364

Swiss Prot

P16662

Accession Number

P16662

Host

Rabbit

Reactivity

Human

Immunogen

This UGT2B7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the N-terminal region of human UGT2B7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UGT2B7

NCBI Official Name

UDP-glucuronosyltransferase 2B7

NCBI Organism

Homo sapiens

Background Reference 01

Joy, M.S., et al. Eur. J. Clin. Pharmacol. 66 (11) :1119-1130 (2010)

Background Reference 02

Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)

Background Reference 03

Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)

Background Reference 04

Woillard, J.B., et al. BrClin Pharmacol 69 (6) :675-683 (2010)

Other Product Names

UDP-glucuronosyltransferase 2B7, UDPGT 2B7,4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGT 2B9, UDPGTh-2, UGT2B7, UGTB2B9

Tested Applications

Protein ID

136727

Physical Properties

Liquid

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