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TOR1A Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq].

NCBI Gene ID

1861

Swiss Prot

O14656

Accession Number

O14656

Host

Rabbit

Reactivity

Human

Immunogen

This TOR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the C-terminal region of human TOR1A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TOR1A

NCBI Official Name

Torsin-1A

NCBI Organism

Homo sapiens

Background Reference 01

Sharma, N., et al. Mov. Disord. 25 (13) :2183-2187 (2010)

Background Reference 02

Kaiser, F.J., et al. Ann. Neurol. 68 (4) :554-559 (2010)

Background Reference 03

Gavarini, S., et al. Ann. Neurol. 68 (4) :549-553 (2010)

Background Reference 04

Granata, A., et al. Eur. J. Neurol. 17 SUPPL 1, 81-87 (2010) :

Other Product Names

Torsin-1A, Dystonia 1 protein, Torsin ATPase-1A, 364-, Torsin family 1 member A, TOR1A, DQ2, DYT1, TA, TORA

Tested Applications

WB

Physical Properties

Liquid

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