SS18L1 Antibody

Product Specifications

Background

Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t (X;18) (p11.2; q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.

NCBI Gene ID

26039

Swiss Prot

O75177

Accession Number

O75177

Host

Rabbit

Reactivity

Human

Immunogen

This SS18L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human SS18L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SS18L1

NCBI Official Name

Calcium-responsive transactivator

NCBI Organism

Homo sapiens

Background Reference 01

Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)

Background Reference 02

Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)

Background Reference 03

Yoshida, T., et al. Int. J. Mol. Med. 24 (4) :539-547 (2009)

Background Reference 04

De Bruijn, D.R., et al. Cytogenet. Genome Res. 112 (3-4), 222-226 (2006) :

Other Product Names

Calcium-responsive transactivator, SS18-like protein 1, SYT homolog 1, SS18L1, CREST, KIAA0693

Tested Applications

Physical Properties

Liquid

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