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NCKPL Antibody

Product Specifications

Background

This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.

NCBI Gene ID

3071

Swiss Prot

P55160

Accession Number

P55160

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NCKPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 641-669 amino acids from the Central region of human NCKPL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

128 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NCKAP1L

NCBI Official Name

Nck-associated protein 1-like

NCBI Organism

Homo sapiens

Background Reference 01

Joshi, A.D., et al. Clin. Cancer Res. 13 (18 PT 1), 5295-5304 (2007) :

Background Reference 02

Weiner, O.D., et al. PLoS Biol. (9), E221 (2007) :

Background Reference 03

Weiner, O.D., et al. PLoS Biol. (2), E38 (2006) :

Background Reference 04

Baumgartner, S., et al. J. Mol. Biol. 251 (1) :41-49 (1995)

Other Product Names

Nck-associated protein 1-like, Hematopoietic protein 1, Membrane-associated protein HEM-1, NCKAP1L, HEM1

Tested Applications

WB

Protein ID

218512111

Physical Properties

Liquid

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