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MDH2 Antibody

Product Specifications

Background

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. [provided by RefSeq].

NCBI Gene ID

4191

Swiss Prot

P40926

Accession Number

P40926

Host

Rabbit

Reactivity

Human

Immunogen

This MDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human MDH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MDH2

NCBI Official Name

Malate dehydrogenase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Rzem, R., et al. J. Inherit. Metab. Dis. 30 (5) :681-689 (2007)

Background Reference 03

Luo, C., et al. J. Biochem. Biophys. Methods 68 (2) :101-111 (2006)

Background Reference 04

Kullberg, M., et al. Mol. Biol. Evol. 23 (8) :1493-1503 (2006)

Other Product Names

Malate dehydrogenase, mitochondrial, MDH2

Tested Applications

WB

Protein ID

215274114

Physical Properties

Liquid

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