CCR4 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

NCBI Gene ID

1233

Swiss Prot

P51679

Accession Number

P51679

Host

Rabbit

Reactivity

Human

Immunogen

This CCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human CCR4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCR4

NCBI Official Name

C-C chemokine receptor type 4

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 03

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 04

Klapa, S., et al. Clin. Exp. Rheumatol. 28 (1 SUPPL 57), 72-80 (2010) :

Other Product Names

C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5, CD194, CCR4, CMKBR4

Tested Applications

Protein ID

1705894

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-89777F 0.1 mL

Rabbit Monoclonal IL-32 Antibody (403) [FITC]

Ask

View Details

RG220377 10 µg

Glucocorticoid Receptor (NR3C1) (NM_001020825) Human Tagged ORF Clone

Ask

View Details

MBS9428908-01 96 Tests

Human Low affinity immunoglobulin gamma Fc region receptor III-B ELISA Kit

Ask

View Details

MBS9428908-02 5x 96 Tests

Human Low affinity immunoglobulin gamma Fc region receptor III-B ELISA Kit

Ask

View Details

PO54657M2 100 µg

Influenza A H1N1 (A/swine/Kansas/00246/2004) Hemagglutinin / HA Protein (His Tag)

Ask

View Details

FON-343 10 Tests

S100A10 - CEN1 FISH Probe

Ask

View Details