MOG Antibody
Product Specifications
Background
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
4340
Swiss Prot
Q16653
Accession Number
Q16653
Host
Rabbit
Reactivity
Human
Immunogen
This MOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the Central region of human MOG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MOG
NCBI Official Name
Myelin-oligodendrocyte glycoprotein
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Boyle, L.H., et al. J. Neurochem. 102 (6) :1853-1862 (2007)
Background Reference 03
Allamargot, C., et al. J. Neurochem. 101 (2) :298-312 (2007)
Background Reference 04
Delarasse, C., et al. J. Neurochem. 98 (6) :1707-1717 (2006)
Other Product Names
Myelin-oligodendrocyte glycoprotein, MOG
Tested Applications
WB
Protein ID
317373391
Physical Properties
Liquid
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