MND1 Antibody
Product Specifications
Background
The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]) . Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
NCBI Gene ID
84057
Swiss Prot
Q9BWT6
Accession Number
Q9BWT6
Host
Rabbit
Reactivity
Human
Immunogen
This MND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the C-terminal region of human MND1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MND1
NCBI Official Name
Meiotic nuclear division protein 1 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 02
Chi, P., et al. Genes Dev. 21 (14) :1747-1757 (2007)
Background Reference 03
Enomoto, R., et al. J. Biol. Chem. 281 (9) :5575-5581 (2006)
Background Reference 04
Tsubouchi, H., et al. Mol. Cell. Biol. 22 (9) :3078-3088 (2002)
Other Product Names
Meiotic nuclear division protein 1 homolog, MND1 {ECO:0000312|EMBL:EAX049641}
Tested Applications
WB
Protein ID
74733462
Physical Properties
Liquid
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