NUBPL Antibody
Product Specifications
Background
Respiratory complex I (NADH:ubiquinone oxidoreductase EC 1.6.5.3) is a large mitochondrial inner membrane enzyme consisting of 45 subunits and 8 iron-sulfur (Fe/S) clusters. NUBPL, or IND1, is an Fe/ S protein that plays a critical role in the assembly of respiratory complex I, likely by transferring Fe/S into the Fe/S-containing complex I subunits (Sheftel et al., 2009 [PubMed 19752196]) .
NCBI Gene ID
80224
Swiss Prot
Q8TB37
Accession Number
Q8TB37
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This NUBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-67 amino acids from the N-terminal region of human NUBPL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NUBPL
NCBI Official Name
Iron-sulfur protein NUBPL
NCBI Organism
Homo sapiens
Background Reference 01
Calvo, S.E., et al. Nat. Genet. 42 (10) :851-858 (2010)
Background Reference 02
Sheftel, A.D., et al. Mol. Cell. Biol. 29 (22) :6059-6073 (2009)
Background Reference 03
Volpi, S., et al. Mol. Psychiatry 14 (11) :1024-1031 (2009)
Background Reference 04
Baranzini, S.E., et al. Hum. Mol. Genet. 18 (4) :767-778 (2009)
Other Product Names
Iron-sulfur protein NUBPL, IND1 homolog, Nucleotide-binding protein-like, huInd1, NUBPL, C14orf127
Tested Applications
WB
Protein ID
116242683
Physical Properties
Liquid
Frequently Asked Questions
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