NUBPL Antibody

Product Specifications

Background

Respiratory complex I (NADH:ubiquinone oxidoreductase EC 1.6.5.3) is a large mitochondrial inner membrane enzyme consisting of 45 subunits and 8 iron-sulfur (Fe/S) clusters. NUBPL, or IND1, is an Fe/ S protein that plays a critical role in the assembly of respiratory complex I, likely by transferring Fe/S into the Fe/S-containing complex I subunits (Sheftel et al., 2009 [PubMed 19752196]) .

NCBI Gene ID

80224

Swiss Prot

Q8TB37

Accession Number

Q8TB37

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NUBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-67 amino acids from the N-terminal region of human NUBPL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NUBPL

NCBI Official Name

Iron-sulfur protein NUBPL

NCBI Organism

Homo sapiens

Background Reference 01

Calvo, S.E., et al. Nat. Genet. 42 (10) :851-858 (2010)

Background Reference 02

Sheftel, A.D., et al. Mol. Cell. Biol. 29 (22) :6059-6073 (2009)

Background Reference 03

Volpi, S., et al. Mol. Psychiatry 14 (11) :1024-1031 (2009)

Background Reference 04

Baranzini, S.E., et al. Hum. Mol. Genet. 18 (4) :767-778 (2009)

Other Product Names

Iron-sulfur protein NUBPL, IND1 homolog, Nucleotide-binding protein-like, huInd1, NUBPL, C14orf127

Tested Applications

Protein ID

116242683

Physical Properties

Liquid

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