GNMT Antibody
Product Specifications
Background
The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia) .
NCBI Gene ID
27232
Swiss Prot
Q14749
Accession Number
Q14749
Host
Rabbit
Reactivity
Human
Immunogen
This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human GNMT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig, Rabbit
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GNMT
NCBI Official Name
Glycine N-methyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 02
Lee, C.M., et al. Gene 443 (1-2), 151-157 (2009) :
Background Reference 03
Boyles, A.L., et al. Genet. Epidemiol. 33 (3) :247-255 (2009)
Background Reference 04
Yen, C.H., et al. Toxicol. Appl. Pharmacol. 235 (3) :296-304 (2009)
Other Product Names
Glycine N-methyltransferase, GNMT
Tested Applications
WB
Protein ID
12644416
Physical Properties
Liquid
Frequently Asked Questions
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