What is the catalog number for FNTA Antibody?

The catalog number for FNTA Antibody is 59-614.

What sizes are available for FNTA Antibody?

FNTA Antibody is available in the following size(s): 400 µL.

Is FNTA Antibody in stock?

FNTA Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

FNTA Antibody

Product Specifications

Background

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13.

NCBI Gene ID

2339

Swiss Prot

P49354

Accession Number

P49354

Host

Rabbit

Reactivity

Human

Immunogen

This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human FNTA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FNTA

NCBI Official Name

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

NCBI Organism

Homo sapiens

Background Reference 01

Lipkin, S.M., et al. Cancer Prev Res (Phila Pa) 3 (5) :597-603 (2010)

Background Reference 02

Fontaine-Bisson, B., et al. J. Mol. Med. 88 (2) :193-201 (2010)

Background Reference 03

Zhou, J., et al. J. Biol. Chem. 284 (15) :9648-9655 (2009)

Background Reference 04

Veluthakal, R., et al. Diabetes 56 (1) :204-210 (2007)

Other Product Names

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA