GPT2 Antibody

Product Specifications

Background

GPT (MIM 138200) and GPT2 (EC 2.6.1.2), also known as alanine transaminases, are pyridoxal enzymes that catalyze the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. By mediating the conversion of these 4 major intermediate metabolites, these transaminases have roles in gluconeogenesis and in amino acid metabolism.

NCBI Gene ID

84706

Swiss Prot

Q8TD30

Accession Number

Q8TD30

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human GPT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GPT2

NCBI Official Name

Alanine aminotransferase 2

NCBI Organism

Homo sapiens

Background Reference 01

Glinghammar, B., et al. Int. J. Mol. Med. 23 (5) :621-631 (2009)

Background Reference 02

Fraser, A., et al. Hepatology 46 (1) :158-165 (2007)

Background Reference 03

Ding, Y., et al. World J. Gastroenterol. 12 (43) :7038-7041 (2006)

Background Reference 04

Martin, J., et al. Nature 432 (7020) :988-994 (2004)

Other Product Names

Alanine aminotransferase 2, ALT2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic transaminase 2, GPT2, AAT2, ALT2