FIGLA Antibody

Product Specifications

Background

This gene encodes a protein that functions in postnatal oocyte-specific gene expression. The protein is a basic helix-loop-helix transcription factor that regulates multiple oocyte-specific genes, including genes involved in folliculogenesis and those that encode the zona pellucida. Mutations in this gene cause premature ovarian failure type 6.

NCBI Gene ID

344018

Swiss Prot

Q6QHK4

Accession Number

Q6QHK4

Host

Rabbit

Reactivity

Human

Immunogen

This FIGLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-137 amino acids from the Central region of human FIGLA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FIGLA

NCBI Official Name

Factor in the germline alpha

NCBI Organism

Homo sapiens

Background Reference 01

Van Dooren, M.F., et al. Curr. Opin. Obstet. Gynecol. 21 (4) :313-317 (2009)

Background Reference 02

Fowler, P.A., et al. J. Clin. Endocrinol. Metab. 94 (4) :1427-1435 (2009)

Background Reference 03

Tormala, R.M., et al. Mol. Cell. Endocrinol. 289 (1-2), 10-15 (2008) :

Background Reference 04

Zhao, H., et al. Am. J. Hum. Genet. 82 (6) :1342-1348 (2008)

Other Product Names

Factor in the germline alpha, FIGalpha, Class C basic helix-loop-helix protein 8, bHLHc8, Folliculogenesis-specific basic helix-loop-helix protein, Transcription factor FIGa, FIGLA, BHLHC8