F2R Antibody

Product Specifications

Background

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq].

NCBI Gene ID

2149

Swiss Prot

P25116

Accession Number

P25116

Host

Rabbit

Reactivity

Human

Immunogen

This F2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human F2R.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

F2R

NCBI Official Name

Proteinase-activated receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Bae, J.S., et al. J. Biol. Chem. 285 (45) :34803-34812 (2010)

Background Reference 02

Motovska, Z., et al. Atherosclerosis 212 (2) :548-552 (2010)

Background Reference 03

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 04

Burch, M.L., et al. J. Biol. Chem. 285 (35) :26798-26805 (2010)

Other Product Names

Proteinase-activated receptor 1, PAR-1, Coagulation factor II receptor, Thrombin receptor, F2R, CF2R, PAR1, TR

Tested Applications

Protein ID

20178318

Physical Properties

Liquid

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