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CENPE Antibody

Product Specifications

Background

Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.

NCBI Gene ID

1062

Swiss Prot

Q02224

Accession Number

Q02224

Host

Rabbit

Reactivity

Human

Immunogen

This CENPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2573-2601 amino acids from the C-terminal region of human CENPE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-572

Calculated Molecular Weight

316 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CENPE

NCBI Official Name

Centromere-associated protein E

NCBI Organism

Homo sapiens

Background Reference 01

Kim, Y., et al. Cell 142 (3) :444-455 (2010)

Background Reference 02

Maia, A.F., et al. Chromosoma 119 (4) :405-413 (2010)

Background Reference 03

Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)

Background Reference 04

Maffini, S., et al. Curr. Biol. 19 (18) :1566-1572 (2009)

Other Product Names

Centromere-associated protein E, Centromere protein E, CENP-E, Kinesin-related protein CENPE, CENPE

Tested Applications

WB

Protein ID

160358869

Physical Properties

Liquid

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