CENPE Antibody
Product Specifications
Background
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.
NCBI Gene ID
1062
Swiss Prot
Q02224
Accession Number
Q02224
Host
Rabbit
Reactivity
Human
Immunogen
This CENPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2573-2601 amino acids from the C-terminal region of human CENPE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
316 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CENPE
NCBI Official Name
Centromere-associated protein E
NCBI Organism
Homo sapiens
Background Reference 01
Kim, Y., et al. Cell 142 (3) :444-455 (2010)
Background Reference 02
Maia, A.F., et al. Chromosoma 119 (4) :405-413 (2010)
Background Reference 03
Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)
Background Reference 04
Maffini, S., et al. Curr. Biol. 19 (18) :1566-1572 (2009)
Other Product Names
Centromere-associated protein E, Centromere protein E, CENP-E, Kinesin-related protein CENPE, CENPE
Tested Applications
WB
Protein ID
160358869
Physical Properties
Liquid
Frequently Asked Questions
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