GEMIN8 Antibody
Product Specifications
Background
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
NCBI Gene ID
54960
Swiss Prot
Q9NWZ8
Accession Number
Q9NWZ8
Host
Rabbit
Reactivity
Human
Immunogen
This GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the C-terminal region of human GEMIN8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GEMIN8
NCBI Official Name
Gem-associated protein 8
NCBI Organism
Homo sapiens
Background Reference 01
Carissimi, C., et al. J. Biol. Chem. 281 (48) :37009-37016 (2006)
Background Reference 02
Carissimi, C., et al. J. Biol. Chem. 281 (12) :8126-8134 (2006)
Other Product Names
Gem-associated protein 8, Gemin-8, Protein FAM51A1, GEMIN8, FAM51A1
Tested Applications
WB
Protein ID
52782795
Physical Properties
Liquid
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