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ADAT1 Antibody

Product Specifications

Background

This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described.

NCBI Gene ID

23536

Swiss Prot

Q9BUB4

Accession Number

Q9BUB4

Host

Rabbit

Reactivity

Human

Immunogen

This ADAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-60 amino acids from the N-terminal region of human ADAT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ADAT1

NCBI Official Name

TRNA-specific adenosine deaminase 1

NCBI Organism

Homo sapiens

Background Reference 01

Dastani, Z., et al. Eur. J. Hum. Genet. 18 (3) :342-347 (2010)

Background Reference 02

Maas, S., et al. Proc. Natl. Acad. Sci. U.S.A. 96 (16) :8895-8900 (1999)

Other Product Names

TRNA-specific adenosine deaminase 1, hADAT1, tRNA-specific adenosine-37 deaminase, ADAT1

Tested Applications

WB

Protein ID

74733201

Physical Properties

Liquid

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