MARH3 Antibody
Product Specifications
Background
MARCH3 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH3 appears to function in the endosomal recycling pathway (Fukuda et al., 2006 [PubMed 16428329]) .
NCBI Gene ID
115123
Swiss Prot
Q86UD3
Accession Number
Q86UD3
Host
Rabbit
Reactivity
Human
Immunogen
This MARH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human MARH3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-505
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MARCH3
NCBI Official Name
E3 ubiquitin-protein ligase MARCH3
NCBI Organism
Homo sapiens
Background Reference 01
Fukuda, H., et al. J. Biochem. 139 (1) :137-145 (2006)
Background Reference 02
Bartee, E., et al. J. Virol. 78 (3) :1109-1120 (2004)
Other Product Names
E3 ubiquitin-protein ligase MARCH3, 632-, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, MARCH-III, RING finger protein 173, MARCH3, RNF173
Tested Applications
WB
Protein ID
59798460
Physical Properties
Liquid
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