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PNMA3 Antibody

Product Specifications

Background

This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. [provided by RefSeq].

NCBI Gene ID

29944

Swiss Prot

Q9UL41

Accession Number

Q9UL41

Host

Rabbit

Reactivity

Human

Immunogen

This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PNMA3

NCBI Official Name

Paraneoplastic antigen Ma3

NCBI Organism

Homo sapiens

Background Reference 01

Wills, N.M., et al. J. Biol. Chem. 281 (11) :7082-7088 (2006)

Background Reference 02

Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005) :

Background Reference 03

Rosenfeld, M.R., et al. Ann. Neurol. 50 (3) :339-348 (2001)

Other Product Names

Paraneoplastic antigen Ma3, PNMA3, MA3

Tested Applications

WB

Protein ID

296452862

Physical Properties

Liquid

Frequently Asked Questions

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