PNMA3 Antibody
Product Specifications
Background
This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. [provided by RefSeq].
NCBI Gene ID
29944
Swiss Prot
Q9UL41
Accession Number
Q9UL41
Host
Rabbit
Reactivity
Human
Immunogen
This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PNMA3
NCBI Official Name
Paraneoplastic antigen Ma3
NCBI Organism
Homo sapiens
Background Reference 01
Wills, N.M., et al. J. Biol. Chem. 281 (11) :7082-7088 (2006)
Background Reference 02
Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005) :
Background Reference 03
Rosenfeld, M.R., et al. Ann. Neurol. 50 (3) :339-348 (2001)
Other Product Names
Paraneoplastic antigen Ma3, PNMA3, MA3
Tested Applications
WB
Protein ID
296452862
Physical Properties
Liquid
Curated Selection
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