AMTN Antibody
Product Specifications
Background
The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]) .
NCBI Gene ID
401138
Swiss Prot
Q6UX39
Accession Number
Q6UX39
Host
Rabbit
Reactivity
Human
Immunogen
This AMTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human AMTN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AMTN
NCBI Official Name
Amelotin
NCBI Organism
Homo sapiens
Background Reference 01
Moffatt, P., et al. Biochem. J. 399 (1) :37-46 (2006)
Background Reference 02
Iwasaki, K., et al. J. Dent. Res. 84 (12) :1127-1132 (2005)
Background Reference 03
Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)
Background Reference 04
Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)
Other Product Names
Amelotin, AMTN
Tested Applications
WB
Protein ID
55976710
Physical Properties
Liquid
Curated Selection
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